Angle of Repose by Wallace StegnerRead about the other entries on the list.
I once attended a lecture series called "How the West Was Written" that included discussion of works by Willa Cather, Raymond Chandler, John Fante, and Stegner. Stegner's Pulitzer-winning 1971 novel is presented as the attempt of a wheelchair-bound historian to capture the lives of his settler grandparents. It's all here: the bravery and adventure of those who explored the West; the sacrifice and the love. Amazing!
Angle of Repose is among Monique Alice's seven top works of Western fiction, Paula Fredriksen's five best books on sin, and Andrea Wulf's six favorite books.