One entry on the list:
Dreamsnake by Vonda McIntyreRead about the other entries on the list.
Why It's Weird: The novel follows a healer through a post-apocalyptic, desert-like landscape, as she looks for a replacement "dreamsnake." Dreamsnake bites produce hallucinations similar to acid trips. So in a sense, what we're looking at here is one long roadtrip dedicated to the pursuit of LSD.
Why It's Required: Dreamsnake swept the awards when it was first published, winning the 1979 Hugo Award, the 1978 Nebula Award, and the 1979 Locus Award. It was also nominated for the 1979 Ditmar Award in International Fiction.
My Book, The Movie: Dreamsnake.